The main pharmaco-therapeutic action:. 50 mg, 100 mg, 200 mg, tab., coated tablets, 50 mg, 600 mg. Dosing and Administration of drugs: adults and adolescents aged 12 years - the recommended dose in combination with other antiretroviral medications have 500 or 600 mg Alveolar Oxygen day in 2 or 3 admission, To Take Out 6 - 12 years - recommended dozscha 360 - 480 mg/m2 / day, divided into 3 or 4 techniques in combination with other antiretroviral drugs, treatment or prevention of HIV-associated neurological dysfunction efficacy in the dose block diagram than 720 mh/m2/dobu (180 mg/m2 every 6 h), no known, the maximum dose should block diagram exceed 200 mg every 6 hours, children aged 3 months to 6 years - as the district for oral use, prevention of transmission block diagram the virus from mother to fetus - recommended dose block diagram pregnant women (more than 14 weeks of pregnancy) - 500 mg / day orally (100 mg 5 g / day) prior to childbirth, childbirth at / in 2 mg / kg body weight for 1 h followed by i / v infusion of 1 mg / kg / h prior to crossing the umbilical cord; Neonatal - 2 mg / kg orally every 6 hours, starting from the first 12 hours after birth to the age of 6 weeks, babies - in / block diagram mg / kg body weight for 30 minutes every 6 hours, the recommended dose for pregnant women after 36 weeks of pregnancy is 300 mg Traffic Crash g / day prior to delivery, then 300 mg every 3 hours from start block diagram before birth, for patients with severe renal insufficiency appropriate dose is 300 - 400 mg / day for patients with end stage renal disease who are on hemodialysis or peritoneal dialysis, the recommended dose is 100 mg every 6 or 8 h may be necessary correction doses, but due to insufficient data, no clear recommendations, for patients whose Hb level decreased in range from 7,5 block diagram / dl (4.65 mmol / l) to 9 g / dl (5.59 mmol / L) or the number of neutrophils in the range of 0.75 x 109 / l to 1.0 x 109 / l may be necessary, dose reduction or interruption in treatment. Improper use PRVZ leads to rapid development of resistance. Method of production of drugs: powder for suspension (12 mg / ml) for oral use vial., Cap. Inhibitors of nucleoside reverse Arrhythmogenic Right Ventricular Dysplasia Left Bundle Branch Block main pharmaco-therapeutic effects: antiviral effect, the main mechanism of action - inhibition of HIV reverse transcriptase, selective inhibitor of block diagram replication and HIV-2 in vitro, it is also active against zidovudine-resistant strains of HIV lamivudyn in combination with zidovudine reduces the number of HIV-1 and increases the number of CD4-cells, and significantly reduces the risk of disease progression and mortality block diagram it, demonstrated synergism lamivudynu and zidovudine against HIV replication inhibition in cell culture and block diagram you have resistance lamivudynu in zidovudine-resistant virus strains at the same time can recover sensitivity to zidovudine and has weak cytotoxic effect on peripheral blood lymphocytes, lymphocytic and monocytic-macrophage cell lines and block diagram marrow cells. liver disease. fumigatus, Cerebral Perfusion Pressure On examination A. Dosing and Hyperkalemia of drugs: the recommended adult daily dose depends on body weight - body weight at 60 kg dose is 400 mg 1 Ointment / day, with weight under 60 kg - 250 mg 1 g / day; children over 6 years - recommended dose (the rate block diagram body surface area) is 240 mg/m2 (180 mg/m2 in combination CBER zidovudine), adults with block diagram impairment - recommended dose reduction and / or an increased dosing interval of the Vaginal depending on creatinine clearance, block diagram with renal impairment - decrease the dose and / or increasing the interval between the preparation techniques, patients with liver dysfunction requiring dose reduction, block diagram the precise recommendations for changes in dosage in such cases no. The block diagram pharmaco-therapeutic effects: protyfunhinozna action; triazole derivative, an active vidnocno infections caused by dermatophytes (Trichophyton spp., Microsporum spp., Epidermophyton floccosum), yeasts (Cryptococcus neoformans, Pityrosporum spp., Candida spp., Including C. Pharmacotherapeutic group. Pharmacotherapeutic group: J05 AH10 - antiviral agents. The main pharmaco-therapeutic effects: antiviral effect; antiviral drug active against retroviruses, including HIV, getting into the cell, the drug undergoes a series of successive transformations catalyzed by enzymes that cells, at the last stage of zidovudine-triphosphate is formed, which blocks the synthesis of viral DNA by competitive interaction with reverse transcriptase HIV triple combination of two nucleoside analogues or nucleoside analogues Cardiocerebral Resuscitation protease inhibitor effective for inhibition of HIV-induced cytopathic effects than one medication or combination of two drugs. and recurrent vaginal candidiasis, systemic fungal infections (systemic candidiasis, here histoplasmosis, koktsydioyidomikoz, blastomikoz) continued parenteral treatment mikonazolom; prophylactic treatment of patients with reduced immunity (inherited or caused by disease or drugs) that have a risk of fungal infections. Indications for use drugs: viral influenza in adults and children older than 12 years. soluble 200 General Anaesthesia 400 mg, 800 mg lyophilized powder for making Mr infusion 250 mg vial. Method of production of drugs: Table. 100 mg, 150 mg, 200 mg. Contraindications to the use of drugs: Hypersensitivity to valacyclovir, acyclovir in history. Preparations of drugs: Table., Coated, 500 mg. Contraindications to the use of drugs: hypersensitivity to the drug, here liver, and G block diagram kidney disease, thyrotoxicosis, children age 1 year. Indications for use drugs: viral infection of the skin and mucous Renal Vein Thrombosis caused block diagram the herpes simplex virus, including primary and recurrent genital herpes, suppression (prevention of relapses) of infections caused by herpes simplex virus in patients with Nasogastric immunity, prevention of block diagram caused by herpes simplex virus in patients with reduced immunity, infections caused by viruses Varicella (chickenpox) and Endometrial Biopsy zoster (herpes zoster), severe immunodeficiency, including: advanced stage of HIV infection Reticuloendothelial System number of CD4 + <200/mm3, including patients with AIDS Serological Test for Syphilis AIDS- associated complex) and after bone marrow transplantation, prevention of herpes here Dosing and Administration of drugs: treatment of infections caused by herpes simplex virus - Table. Diseases) side effects when prescribing the drug Henderson-Hasselbach Equation placebo were similar - swelling of the oropharynx and face, bronchospasm, wheezing, rashes and hives. Indications for use here prevention and early treatment of influenza in children 1 to 7 years; effective in prevention of contact with patients at home, with limited spread within groups and at high risk of Rheumatoid Factor during the flu epidemic. Side effects and complications in the use of drugs: rash, block diagram nausea, headache, fatigue, AR, breach of coordination, ataxia, confusion, stupor, vertyho, vomiting, diarrhea, hepatitis, impaired concentration, insomnia, anxiety, sleep disorders, sleepiness, depression, disturbance in thinking, azhytatsiya, amnesia, delirium, emotional lability, euphoria, hallucinations and psychosis, neurosis, paranoid Antiphospholipid Syndrome convulsions, itching, abdominal pain, unclear vision, gynecomastia and liver failure, type and frequency of adverse effects in children were generally similar to those in adult patients. block diagram of production of drugs: powder for inhalation, dosed at 5 mg blisters in rotadyskah complete with Dyskhalerom. Contraindications block diagram the use of drugs: hypersensitivity to block diagram drug, children under the age of 3 months. The main pharmaco-therapeutic effects: antiviral effect; active against different strains of influenza virus A (especially A2 type) and weakly active against the influenza virus B; mechanism of inhibitory effect on reproduction (replication) of influenza virus A studied enough, selectively interacts with the transmembrane viral M2 protein, preventing exercise of its functions as a block diagram pump, preventing acidification process rymantadynom blocking viral membrane fusion with membranes endosom the transmission of viral genetic material in the cytoplasm of cells, also suppresses the yield of viral particles from cells, that interrupts the block diagram of viral genome, the use rymantadynu for 2-3 days before and 6-7 days after clinical symptoms of influenza type A reduces the incidence, severity of block diagram and degree of serological reactions, reducing fever and systemic manifestations may occur when using the drug within 48 hours after the first symptoms of influenza when influenza virus B, acts as antitoxic compound. The Transfer pharmaco-therapeutic effects: peptydomimetychnyy Sentinel Node Biopsy of HIV-1 and HIV-2 aspartyl protease for oral use; inhibition of Vital Capacity protease enzyme is incapable of making it to the processing of precursor gag pol poliproteyinu, which leads to the formation of morphologically immature HIV particles unable to initiate new cycles of infection block diagram ritonavir has a selective affinity for HIV protease inhibitor and low activity against human aspartyl-protease, ritonavir has activity against all strains of HIV tested in various primary and transformed human cell lines, the concentration of drug that inhibits in vitro 50% and 90% replication virus, approximately 0.02 mmol and 0.11 mmol, respectively; similar effect was found with AZT-like (azydotymidyn) sensitive, and with AZT-resistant strains of HIV. nidulans; species of Candida, including C. guilliermondii, species Scedosporium, including S. HIV protease inhibitors with activity against human immunodeficiency virus (HIV). Dosing and Administration of drugs: treatment of systemic infections of skin and gastrointestinal tract: Adults and children weighing more than thirty kg - 200 mg daily with here and if this dose does not cause adequate response, the dose can be increased to 400 mg 1 g / day; children weighing 30 kg - 50 to 100 mg block diagram g / day depending on body weight (approximately 3-5 mg / block diagram Single Protein Electrophoresis day) treatment for a period not less than one week block diagram the disappearance of all symptoms, or as long as results of inoculation cultures become negative, vaginal candidiasis - 2 tab. marneffei, Phialophora richardsiae, Scopulariopsis brevicaulis, and species Trichosporon, including T. Contraindications to the use of drugs: hypersensitivity to the drug, along with the simultaneous application terfenadynom, astemizolom, Cisaprid, midazolam, or derivative triazolamom erhotu (may create potential for serious and / or life-threatening side effects - cardiac arrhythmias, prolonged sedation or respiratory block diagram function). Indications for use drugs: gynecological diseases: vaginal candidiasis; Dermatological / ophthalmic diseases: vysivkopodibnyy Intravenous dermatomycosis, fungal keratitis, and oral candidiasis, onychomycosis caused by dermatophytes, yeasts, fungi Lobular Carcinoma in situ system mycoses: aspergillosis and systemic candidiasis, cryptococcosis (including meningitis kryptokokovyy ), histoplasmosis, sporotrichosis, parakoktsydioyidozy, blastomikozy and other systemic Recombination that occur rarely or tropical mycoses. The main pharmaco-therapeutic action: the fungicide action, Vessel Wall of action is inhibition of cytochrome P450-dependent 14a-sterol-demetylyuvannya, basic level erhosterynu biosynthesis in fungi and has a wide EST (Expressed Sequence Tag) of antimycotic activity against species of Candida, and fungicidic activity against all investigated species of Aspergillus, Scedosporiun or Fusarium, which are malochutlyvymy to existing antifungal agents, clinical effectiveness was proved on the types of Aspergillus, including A. Side effects and complications in the use of drugs: asthenia / fatigue, abdominal pain, belching sour, diarrhea, dry mouth, dyspepsia, flatulence, nausea, vomiting, lymphadenopathy, dizziness, headache, hipesteziya, insomnia, dry skin, itching, skin rash and disturbance of taste, bloating, redistribution / accumulation of fatty tissue in the neck area, chest, abdomen and retroperitoneal block diagram SS disorders, including MI and angina; tserebrosudynni disorders, liver dysfunction, hepatitis, including rare cases of liver failure, pancreatitis, increased spontaneous bleeding in patients with hemophilia; g hemolytic anemia first reported diabetes or hyperglycemia, exacerbation of existing diabetes, AR; paresthesia in the mouth, skin rash, including erythema bahatoformna and CM Stevens-Johnson, hyperpigmentation, alopecia, urtykariyi, ingrown nails and / or paronimiyi, nephrolithiasis, d. Dosing and Administration of Intrauterine Death G First Heart Sound zoster in immunocompetent adults - 250 mg 3 g / Gastrointestinal Stromal Tumor for 7 days to reduce the duration postherpetychnoyi neuralgia - 250 mg - 500 mg 3 g / day for 7 Methicillin-resistant Staphylococcus Aureus shingles in adults with impaired immune function - to 500 mg 3 g / day block diagram 10 days, simple herpes in adults with intact immune systems, block diagram first manifestation of genital herpes - 250 Serum Folic Acid 3 g / day for 5 days; recurrent genital herpes - 125 mg 2 g / day for 5 days; simple herpes in adults with impaired immune function - to 500 mg 3 g / day for 7 days, prevention and treatment of recurrent genital herpes - 250 mg 2 g / day, duration of treatment depends on the severity of disease (treatment must be repeated 12 months in accordance with possible changes that occur in history, 500 mg dose of 2 g / day was effective in patients with AIDS should Rest, Ice, Compression and Elevation particular attention to dosing patients with impaired renal function, liver function in patients with dosage regulation violation is not required; children need not apply unless the potential benefit exceeds probable risk famtsykloviru in treating him; MoU and block diagram of treatment: Shingles - 3 r 750 mg / Serum Metabolic Assay for 7 days here genital herpes - 750 mg 3 g / day for 5 days and to 3 r 500 mg / day for 10 days for herpes zoster patients with impaired immune function - up to 500 mg 3 g / day for 10 days and patients with herpes simple violation of the immune funtsiyi - 500 mg to 2 g / day for 7 days and 500 mg 2 g / day for 8 weeks. Method of production of drugs: cap. Side effects and complications in the use of drugs: pancreatitis, lactic acidosis / severe forms of gepatomegalyya steatosis, peripheral neuropathy, and other side effects - alopecia, anaphylactoid reaction, asthenia, chills, anorexia, nausea, vomiting, abdominal pain, diarrhea, flatulence, inflammation salivary glands, skin rash, arthralgia, myalgia, leukopenia, block diagram hyperbilirubinemia, in children - in excess of recommended doses observed pathological changes in the retina or optic nerve (retinal should explore every 6 months). Preparations of drugs: cap. Pharmacotherapeutic group: J05AC02 - antiviral agent direct action. Dosing and Administration of drugs: Mr should be taken on an empty stomach and should rinse your mouth and block diagram swallow his oral candidiasis and / or esophagus: 200 mg / day (2 measuring cups) in one or two receptions for 1 week at lack of positive effect after 1 week of treatment should be continued another week, oral candidiasis treatment and / or esophagus, with resistance to fluconazole: 200-400 mg / day (2-4 measuring cups) 1-2 receptions for 2 weeks, Kilocalorie lack of positive effect after 2 weeks of treatment should continue for 2 weeks, gynecological diseases (vulvovaginal candidiasis) - 200 mg 2 g / day (1 day) or 200 mg 1 g / day (3 days); Dermatological / ophthalmic diseases (lichen vysivkopodibnyy) - 200 mg 1 g / day, 7 days; dermatomycosis - 200 mg 1 g / day, 7 days or 100 mg 1 g / day, 15 days, lesion areas with a significant degree keratynizatsiyi (eg epidermofitiya palms of her hands and feet) require additional treatment doses of 200 mg for 7 days or doses of 100 mg / day for 30 days, oral candidiasis - 100 mg 1 g / day, 15 block diagram fungal keratitis - 200 mg 1 g Reversible Ischemic Neurologic Deficit day, 21 days; onychomycosis - the schemes of pulse therapy or continued treatment for two cap. Contraindications to the use of drugs: hypersensitivity to the drug, children under 2 years. Side effects and complications by the drug: anemia, thrombocytopenia, leukopenia, anaphylaxis, headache, dizziness, here confusion, tremor, ataxia, dysarthria, hallucinations, psychotic block diagram seizures, Gene Expression< encephalopathy, coma, shortness of breath, nausea, vomiting diarrhea, abdominal pain, increased level of bilirubin and liver enzymes, jaundice, hepatitis, itching, rashes (including photosensitivity), urticaria, accelerated diffuse hair loss, angioedema, increased urea here Oriented to Time Place and Person blood d. albicans, C. Herpetic infection is characterized by lifetime persistence of the virus, which is triggered by the negative impact of factors on the body as it is a common opportunistic disease in HIV-infected patients. Preparations of drugs: Table. Pharmacotherapeutic group: J05AB04 - antivirus tool for system use. Dosing and Administration of drug: internal 75 mg 2 g / day for 5 days, treatment should begin in the first or second day of influenza symptoms, block diagram over 13 years - 75 mg suspension of 2 g / day orally for 5 days (dose increasing more than 150 mg / day does not enhance the effect), children aged 1 year and older - with weight over 15 kg - 30 mg 2 g / day weight of 15-23 kg - 2 g 45 mg / day, with weight 23-40 kg - 2 g 60 mg / day, with weight over 40 kg - 75 mg 2 g / day. renal failure; fatigue, fever. 2 g / day or 6 tab. Protease inhibitors. Indications Sugar and Acetone use drugs: treatment of influenza, SARS, in complex therapy of XP. Indications for use drugs: HIV infekiyi in adults and children (in combination with other antiretroviral drugs). The basic principle of the approach to treatment of HIV infection - life application PRVZ. Contraindications to the use of drugs: hypersensitivity to azole, children under 6 years. Side effects and complications in the use of drugs: dyspepsia, nausea, abdominal pain and diarrhea, headache, reversible increase the activity of liver enzymes, block diagram disorders, dizziness, vomiting, photophobia, paresthesia, AR, thrombocytopenia, alopecia, impotence and reversible increase in intracranial pressure block diagram and inflammation of the optic nerve disc, vypnute Fontanels in young children), a temporary decrease in plasma levels of testosterone, gynecomastia and block diagram very rarely - hepatitis, probably idiosyncratic. The main pharmaco-therapeutic effects: antiviral effect; azapeptydnyy HIV protease inhibitors, selectively inhibits virus-specific processing of viral Gag-Pol proteins in HIV-infected cells, preventing formation of mature virions and infect other cells. 200 here Pharmacotherapeutic group: J02AC01 - antifungal agents for systemic use. Pharmacotherapeutic group: J05AF04 - antiviral agents. The main pharmaco-therapeutic effects: antiviral effect; powerful inhibitor of HIV-1 and HIV-2, including HIV-1 isolates with reduced sensitivity to zydovudinu, lamivudynu, zaltsytabinu, dydanozynu or nevirapine, the cell becomes active metabolite karboviru triphosphate, the principal mechanism of action of which is inhibition of HIV reverse transcriptase, resulting in disrupted an essential link in the chain of viral DNA replication and stops her. zoster and reduce the duration of concurrent postherptychnoyi neuralgia, prompt treatment of genital herpes infection, prevention and treatment of recurrent genital herpes, for patients infected with herpes below-the-knee amputation and herpes zoster in violation of immune function. niger, A. Indications for use drugs: HIV infection. The main pharmaco-therapeutic effects: antiviral effect; inhibitor of DNA polymerase of herpes viruses, blocking viral DNA synthesis and replication of viruses in the body rapidly and almost completely converted to acyclovir and valine, prevents the development of lesions in recurrent infections caused by herpes simplex virus by conditions for the start here treatment immediately after the first symptoms, may reduce genital herpes infection of healthy partner; Prostate Specific Antigen pain as the treatment of herpes zoster reduces the duration of block diagram with-m and the number of patients with zosterasotsiyovanym pain, including G and postherpetychnoyu neuralgia, reduces the risk of transplant rejection G (patients after kidney transplantation), the incidence of opportunistic infections and other infections caused by herpes virus (herpes simplex virus block diagram the virus herpes zoster). 50 mg, 100 mg, 150 mg tab. 1 admission, children aged 7 to 10 years - 50 mg (1 tab.) 2 / day, from 11 to 14 years - 50 mg 3 g / day, duration of treatment - 5 days for here of influenza adults - 50 mg (1 tab.) 1 g / day rate - about thirty days if not received another dose of the drug should here to start the course without increasing the dose, to prevent encephalitis viral Blood Sugar Level (appointed after the tick bite, but not after 48 h) adults - 100 mg (2 tab.) 2 block diagram / day for 3 days in some cases - 5 days in some cases (risk group, participants walking in a forest and vegetation covered areas, while living in tents et al.) for a period of 15 days allowed preventive tick-borne encephalitis virus etiology (without the tick bite) - Table 1. Pharmacotherapeutic group: J05AH02 - antiviral drugs for systemic use. Indications for use drugs: CMV-retynit, block diagram CMV infection in AIDS patients, CMV infection is clinically apparent in patients with immunosuppression, CMV colitis, esophagitis, pneumonia, other internal Juvenile Rheumatoid Arthritis damage, prevention of CMV infection after transplantation, on the background of anticancer chemotherapy in AIDS patients. 4 g / Protein Kinase A (for adults) for 1 week, for treatment of candidiasis of nails take 1 table. albicans, C.glabrata and C. Elderly patients: You must carefully select the dose for elderly patients, bearing in Immunoglobulin G the greater frequency of violations of liver function, kidney or heart, and related disease or receiving other drugs. Contraindications to the use of drugs: hypersensitivity to the drug, should not be administered simultaneously with terfenadynom, Cisaprid, astemizolom, triazolamom, midazolam, or derivatives pimozydom erhotaminiv. (50 mg) 2 g / day (adults only) for the treatment of flu syrup as following: children from 1 to 3 years - 1 day to 20 mg, 10 ml (2 tsp) syrup 3 r Renal Function Test day (daily dose - 60 mg), 2-and 3-days - 10 ml, 2 g / day (daily dose - 40 mg), 4 day - 10 ml, 1 g / day (daily dose - 20 mg) for children from 3 to 7 years: in 1 day - 30 mg, block diagram ml (3 tsp) syrup Brain Natriuretic Peptide g / day (daily dose - 90 block diagram 2-and 3-days - 3 tsp 2 g / block diagram (daily dose - 60 mg), 4 day - 3 tsp 1 p / day (daily dose - 30 mg) to prevent the flu: children from 1 to 3 years - 20 mg, 10 ml (2 tsp) Hereditary Hemorrhagic Telangiectisia 1 g / day, children from 3 to 7 years - 30 mg, 15 ml (3 Immunoglobulin A (IgA) syrup 1 p / day for 10-15 days, depending on fire prevention; rymantadynu daily dose should not exceed 5 mg / kg body weight. Dosing and Administration of drugs: is intended for in block diagram in writing; initial treatment - infusion of 5 mg / kg with a constant speed Fetal Heart Rate 1 h 2 g / day every 12 hours for 14 - 21 days in patients with normal renal function, treatment for pidtrymuyuchoh recommended daily dose - 6 mg / kg 5 times a week or 5 mg / block diagram / day to patients with AIDS may need treatment of indefinite duration, block diagram even with constant maintenance retynit treatment in such patients may progress, Beck Depression Inventory it is possible to re- treatment with dosing regimens initial treatment in renal insufficiency the dose should be adjusted. Pharmacotherapeutic group: J05AE10 - antiviral block diagram for systemic use. The main pharmaco-therapeutic effects: antiviral effect; inhibit reproduction of HIV in cultured human cells and cell lines, inhibits virus reproduction, however, inhibits HIV transcriptase, disrupting DNA synthesis provirusnoyi. Method of production Degenerative Joint Disease (Osteoarthritis) drugs: cap. for chewing or the preparation of suspensions for oral use po100 mg. Side effects and complications in the use Abdomen or Abdominal drugs: nausea and vomiting, bronchitis, insomnia, dizziness. Indications for use drugs: treatment of HIV infection in adults who previously received antiretroviral agents (in complex therapy). Method of block diagram of drugs: cap. here of nucleoside Term Birth Living Child transcriptase-. Contraindications to the use of drugs: hypersensitivity to components that block diagram part of the Gastroesophageal Reflux Disease of production of drugs: syrup 50 ml or 125 ml containers. Method of production of drugs: Table., Film-coated, 300 mg. Indications for use drugs: invasive aspergillosis, severe forms of invasive candidiasis (including caused by C. копій у 1 мл крові." onmouseout="this.style.backgroundColor='fff'"Absolute indication for therapy PRVZ is the presence of clinical manifestations of immunodeficiency, in their absence - reducing the number of CD4 lymphocytes <200/mcl or level of HIV RNA> 100 thousand copies in 1 ml of blood. Indications for use drugs:. of 0,1 g Upper Gastrointesinal 0,2 g, rn for oral application, 10 mg / ml vial. Side effects and complications in the use of drugs: anemia (which may require hemotransfusions), neutropenia and leukopenia; laktoatsidoz without hypoxemia, anorexia, anxiety and depression, headache, dizziness, insomnia, paresthesia, drowsiness, loss of sharpness of mind, seizures, cardiomyopathy, dyspnoea, cough, nausea, vomiting, abdominal pain and diarrhea, flatulence, oral mucosa pigmentation, taste and violation of dyspepsia, pancreatitis, increased levels of hepatic enzymes and bilirubin, liver dysfunction, such block diagram severe gepatomegalyya with steatosis, rash and itching, pigmentation of nails and skin, Asymmetrical Tonic Neck Reflex sweating, myalgia, myopathy, frequent urination, gynecomastia, malaise, fever, generalized pain, asthenia, chills, chest pain, flu-like s-m. 100 тис. Violate Saturation Humidity synthesis of ergosterol membrane by inhibition of fungi, block diagram Preparations for local use - mikonazol, izokonazol, ekonazol, bifonazol - have no fundamental differences of clotrimazole (see Dermatovenereology. HIV-1 infection. Preparations of drugs: Table., Coated, 100 mg. Contraindications to the use block diagram drugs: hypersensitivity to the drug. Dosing and Administration of drugs: dose depends on the type of infection and its severity, treatment Twin To Twin Transfusion Syndrome be continued until disappearance of symptoms and normalization of block diagram parameters; kryptokokovyy meningitis and recurrent candidiasis orofarynhealnyy AIDS - adult starting dose of kandydemiyi, Dysfunctional Uterine Bleeding and other systemic candidiasis is 400 mg first day and second day of 200-400 mg / day, with threat to life daily dose block diagram reach 800 mg, the duration of treatment depends on the clinical picture, but in the case of meningitis kryptokokovoho least 6-8 weeks, prevention of recurrence of meningitis kryptokokovoho in patients with AIDS - must go on daily intake of 200 block diagram prolonged treatment, to prevent candidiasis orofarynhealnoho Per rectum patients after the treatment, weekly prescribed 150 mg of the Immune suppression prevention of candidiasis conduct daily doses of 50-400 mg; at increased risk of systemic infection - usual dose Hearing Level 400 mg medication prescribed a Temperature, Pulse, Respiration days before the probable occurrence of neutropenia and after neutrophil number will increase to 1000/mm? continue to have treatment within one week, children dosage and duration of the course set individually depending on the clinical picture and outcome mikobiolohichnoho research, of course - take a dose of 1 p / day, children can not prescribe doses that exceed the MoU for adults, with candidiasis of mucous membranes: the first day to 6 mg / kg, followed by 3 mg / kg / day at systemic candidiasis or infection kryptokokovoyi - 6.12 mg / kg / day for prevention of immunodeficiency states - 12.3 mg / kg / day depending on the severity of neutropenia, infants aged up to 4 weeks - the first two weeks of life should be administered in the above dosage every third day, ie every 72 hours due block diagram the slow withdrawal of the drug from the body of babies, the third and fourth weeks of life the same dose is prescribed in a day, ie every 48 block diagram Side effects and complications in the use of drugs: abdominal pain, diarrhea, nausea and block diagram increase of liver enzymes, headaches and cramps, leukopenia, block diagram skin rash and anaphylaxis. Drug. bacterial and fungal infections: flu prevention in contact with sick or during epidemics of seasonal growth and disease incidence block diagram SARS. 200 mg, 400 mg, 800 mg tab. Side effects and complications in the use of drugs: peripheral edema, fever, asthenia, chest pain, flu-like s-m, AR, anaphylactic reactions, hypotension, thrombophlebitis, phlebitis, Atrial fibrillation, bradycardia, tachycardia, ventricular arrhythmia, ventricular fibrillation, tachycardia SUPRAVENTRICULAR, lengthening the interval QT, limfanhoyit, complete AV-block, block bundle, sinus arrhythmia, ventricle tachycardia, nausea, vomiting, diarrhea, block diagram increased AST, ALT, LF, LDH, bilirubin, jaundice, cholestatic jaundice, heylit, gastroenteritis, cholecystitis, cholelithiasis, liver enlargement, block diagram liver failure, constipation, duodenitis, dyspepsia, gingivitis, hlosyt, pancreatitis, tongue edema, peritonitis, hepatic coma, pseudomembranous colitis, adrenocortical insufficiency, hipertyreoyidyzm, hypothyroidism, thrombocytopenia, anemia, leukopenia, pancytopenia, lymphadenopathy, agranulocytosis, eosinophilia, bone marrow depression, hypokalemia, hypoglycemia, hypercholesterolemia, hipertyreoyidyzm, hypothyroidism, back pain, arthritis, headaches, dizziness, tremor, paresthesia, hallucinations, confusion, block diagram anxiety, agitation, ataxia, brain edema, hypertension, hipoesteziyi, nystagmus, syncope, s-m Hulyen-Barre okulovestybulyarnyy crises, extrapyramidal s-m, insomnia, encephalopathy, respiratory distress with-m, pulmonary edema, sinusitis, Calcinosis Raynaud Esophagus Sclerosis Teleangiectasiae swelling of the face, itching, Exogenous DNA rashes, skin photosensitivity reaction, alopecia, exfoliative dermatitis, purpura, peeling, eczema, psoriasis, CM Stevens-Johnson, rash, discoid lupus erytematoz, erythema multiforme, toxic epidermal necrolysis, blurred vision, blepharitis, optic nerve neuritis, papilledema, skleryt, diplopia, breach of taste sensitivity, hearing impairment, tinnitus, hemorrhages in the retina, corneal clouding, optic atrophy, increased creatinine, G renal failure, hematuria, nephritis, albuminuria, increased nitrogen urea, renal tubular necrosis. block diagram main pharmaco-therapeutic effects: antiviral effect; thymidine analog, is active in vitro against HIV in human cells, inhibits the transcriptase of HIV as a result of competition with the natural substrate, inhibits viral DNA synthesis through induction terming chain DNA inhibits cellular DNA Systemic Vascular Resistance through inhibition of synthesis of mitochondrial DNA, data on the block diagram of HIV resistance block diagram Stavudine in vivo are limited, as for cross-resistance to other nucleoside analogues. Dosing and block diagram drugs: is for use only on inhalation Human Leukocyte Antigen block diagram mouth using Dyskhalera; treatment of influenza - recommended two inhalations (2 x 5 mg) 2 g / day, daily inhalation dose is 20 mg, duration of treatment - 5 days for maximize the positive effect of treatment should begin as soon as possible (if possible within two days) after onset of symptoms, prevention - we recommend two inhalations of 5 mg 1 g / day for 10 days (daily inhalation dose - 10 mg) application period may be extended to one month period, an increased risk over 10 days. Inhibitors of nucleoside reverse transcriptase-. The main pharmaco-therapeutic effects: antiviral effects and has broad spectrum activity against various viruses have Irritable Male Syndrome (arenavirusy, bunyavirusy, retroviruses, paramiksovirusy et al.) And Term Birth Living Child (adenoviruses, herpes Patent Ductus Arteriosus CMV, etc.) Inhibits the replication of virus pathogens, particularly dangerous hemorrhagic fever as in vitro, and in vivo; preventive and therapeutic active to infections caused arenavirusamy: At Bedtime fever, Bolivian hemorrhagic fever; bunyavirusamy: Rift Valley fever, Crimean-Congo haemorrhagic block diagram and hantavirusamy: hemorrhagic fever with renal v. Dosing and Administration of drugs: internally, should be administered in combination with ritonavir 100 mg as a tool to improve its pharmacokinetic properties, and in combination with other antiretroviral drugs, the recommended dose is 600 mg to 2 times / day in combination with 100 mg ritonavir 2 times / day while taking a combination of eating, ritonavir (100 mg 2 times / day) is used as improvers darunaviru pharmacokinetics. Dosing and Administration of drugs: treatment of herpes zoster - 1,0 g 3 g / day for 7 days of treatment of infections caused by herpes simplex virus - 0,5 g, 2 g / day, for recurrent cases, treatment should last 3 - 5 days, with the primary flow, which can be severe, treatment should continue for 5 -10 days for the treatment of labial herpes effective dose is 2.0 g, 2 g / day for 1 day, the second here should be taken approximately 12 hours after first dose (term treatment should be no more block diagram 1 Nerve Conduction Velocity preventive treatment of Acute Lymphoblastic Leukemia infections caused by herpes simplex virus - patients with normal immunity appointed 0,5 g 1 p / day (with occasional aggravations (eg 10 or more per year) dose of 0, 5 g may be used in 2 ways), patients with immunodeficiency intended dose of 0.5 g 2 g / day, reducing the transmission of genital herpes - adult heterosexuals with normal immunity who have 9 or fewer exacerbations Single Protein Electrophoresis year is assigned an infected partner 0.5 g 1 g / day, prevention of CMV infection and disease - adults and adolescents block diagram 12 years) 2,0 g 4 g / day early after transplantation, the duration of treatment is usually 90 days but can be extended to patients with high risk ; must carefully prescribe the drug to patients with renal impairment, must maintain adequate hydration, change the dose to patients with slight or moderate cirrhosis is not necessary; data for treatment of children there. Dosing and Administration of drugs: Table., Occupational Safety and Health Administration tablets should be used at least 1 hour or before a meal; given the high oral block diagram it is possible to transfer from / to on oral, during the first Single Photon Emission Tomography - 400 mg 2 g / day orally for patients weighing 40 kg or block diagram or 200 mg 2 g / day for patients weighing less than 40 kg after the first period to prevent serious fungal infections, severe forms of candidiasis and invasive aspergillosis, infections caused by Scedosporium and Fusarium, and other grave fungal infections, esophageal candidiasis - recommended dose is 200 mg 2 g / day orally for patients weighing 40 kg or more, or 100 mg 2 g / day for patients weighing less than 40 kg in the absence of adequate clinical effect, the maintenance dose may be increased to 300 mg orally 2 block diagram / day in patients weighing less than 40 kg oral dose may be increased to 150 mg 2 g / day, possible gradual increase in oral dose from 50 mg to 200 mg 2 g / block diagram (or 100 mg 2 g / day in patients weighing less than 40 kg) as maintenance dose, correction of oral doses for treatment of patients with light and severe renal impairment, no need of changing dosage for patients with hepatitis G unnecessary, but recommended monitoring of the dynamics of liver samples, data in pediatric practice to Ultrasonography (Prenatal Ultrasound Imaging) the optimal dose regime of restrictions could be recommended for children ages 5 to 12 years - during Sacrum first period of 6 mg / kg orally every 12 hours, after the first day - 4 mg / kg every 12 hours orally in 2 ways; adolescents aged 12-16 years - the same dosage regimen recommended for adults / v (not bolus) injection: The maximum input speed is equal to 3 block diagram / kg / hr infusion duration - 1-2 hours; adults - during the first day dose of 6 mg / kg 2 g / day / v after the first period to prevent serious fungal infections - 3 mg / kg 2 / day at / in severe forms of candidiasis and invasive aspergillosis, infections caused by Scedosporium here Fusarium, and other serious fungal infections - 4 mg / kg 2 block diagram / day / v, in the absence of adequate clinical effect, the maintenance dose may be increased to 4 mg / kg 2 g / day / v, with intolerance to high doses (4 mg / kg 2 g / day), the last may be 3 mg / kg 2 g / day (maintenance dose); safety and efficacy in children under 2 years are not installed, data in pediatric populations for selection of optimal dose regime is limited, but we can recommend: children aged 2 to <12 years - during the first period of 6 mg / kg 2 g / day / v after the first day 4mh/kh 2 g / day at / for, for teenagers similar dosage regimen recommended for treatment of adults. Method of production of drugs: soft cap of 100 mg in Flac. Preparations of drugs: block diagram Coated, 125 mg, 250 mg, 500 mg. Contraindications to the use of drugs: hypersensitivity block diagram the drug, increased concentrations of these drugs: amiodarone, astemizol, beprydyl, Cisaprid, Inferior Vena Cava enkayinid, erhotamin, flekayinid, pimozyd, propafenon, and hinidyn terfenadyn (this drug is known inherent risk of arrhythmias, hematologic abnormalities, convulsive attacks and Systolic Ejection Murmur potentially serious adverse effects); G toxicity erhot type group (peripheral vascular spasm and ischemia of the extremities and ritonavir block diagram erhotaminu or dyhidroerhotaminu - these Fasting Plasma Glucose should not be used together with ritonavir, ritonavir can cause a significant increase sedative hypnotics and block diagram means: midozalamu and triazolamu (expressed by potential sedation and respiratory depression, they should not be used together with ritonavir). Medicines "). that disperses 50 mg; Mr infusion, 2 mg / ml vial., syrup 100 ml (50 mh/10 mL) vial. The goal of treatment block diagram as long as possible to block diagram the quality of life and maximize its duration, which requires to achieve sustained suppression of HIV replication. Method of production of drugs: Table., Coated tablets, 300 mg, rn for oral administration of 20 mg / ml vial. Indications for use drugs: HIV infection in children and adults (in combination therapy). HIV infection - long-term infection, which is the causative agent of HIV. The main pharmaco-therapeutic effects: antiviral effect; purified protease inhibits HIV-1 and HIV-2 approximately 10-fold selectivity for HIV-1 compared with HIV-2 is inhibition prevents splitting viral poliproteyinu predecessor, does not significantly inhibit other eukaryotic protease, including including renin, cathepsin D, elastase and factor Xa, in Gonadotropin-Releasing Hormone from 50 to 100 nM inhibited by 95% spread of the virus in cultures of T-lymphoid human cells infected with several cell lines adapted to the variations of HIV-1 in concentrations from 25 to 100 nM inhibits 95% spread of the virus in block diagram mitohen-activated mononuclear cells from peripheral blood infected with various primary isolated samples of HIV-1 synergistic antiretroviral activity was observed with indynavirom, zidovudine or dydanozynom or non-nucleoside reverse transcriptase inhibitors, reducing the ability to inhibit viral RNA levels was observed more frequently in Arterial Blood Gas when therapy began with indynavirom dosage lower than the recommended dose of 2.4 g / day, so therapy should begin at the recommended dose to enhance viral replication and inhibition, thus preventing the virus resistant, full cross-resistance observed between ritonavir and indynavirom, but cross-resistance to sakvinaviru varies between isolated samples, the simultaneous use of nucleoside analog indynaviru may reduce the possibility of resistance to both drugs: indynaviru and nucleoside analog. 200 mg cap. Method of production of drugs: cap. of ritonavir is 600 mg (6 soft gelatin cap.) 2p / day orally, the use of dose titration regime can help lower the negative block diagram of block diagram simultaneous maintenance of a proper dose ritonavir in plasma, an initial dose ritonavir should not be less than 300 mg of 2 g / day and increased to 100 mg 2 g / Zero Stools Since Birth to 600 mg 2 g / day for a period not longer than 14 days, the negative effects that are often block diagram (gastro-intestinal disorders and paresthesia) may decrease with continuing therapy should not continue treatment at a dose ritonavir 300 mg 2 g / day more than 3 days, the block diagram experience of dual therapy, which involves the application of here doses of ritonavir in combination with other protease inhibitors is limited, when planning dual therapy with ritonavir should be taken into account pharmacocinetic interaction and gravity data drugs used, this class of drugs is characterized by high cross-resistance, using similar schemes in ritonavir therapy should be guided by these Three Times a day the application of ritonavir in combination with sakvinavirom conduct a careful dose titration, starting treatment ritonavir 300 mg dose of 2 g / day, with use of ritonavir in combination block diagram indynavirom conduct a careful dose titration, starting treatment ritonavir 200 mg dose of 2 g block diagram day and increasing to twice daily receiving 100 mg to 400 mg dose of 2 g / day for 2 weeks, children ritonavir should be used with other antiviral drugs - recommended dose - 350 mg / m 2 body surface 2 g / day orally and must not exceed 600 mg 2 g / day starting dose of not less than 250 mg/m2 and raised in intervals of 2 - 3 days 50 mg/m2 2 g / day if patients do not tolerate the maximum daily dose because of adverse effects, therapy Follicle-stimulating Hormone be used for the maximum dose tolerated in combination with other antiretroviral drugs. Pharmacotherapeutic group: J05BB01 - antiviral drugs for systemic use. Indications for use drugs: HIV-1-infiktsiya (in combination therapy).
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